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What Is Trulicity
Trulicity is a prescription injectable medication used to improve blood sugar control in adults with type 2 diabetes. Here are some key facts about Trulicity: Buy Trulicity online
- It is a GLP-1 receptor agonist that regulates blood sugar by stimulating the release of insulin, slowing digestion, and suppressing appetite.
- Trulicity is the brand name of the generic drug dulaglutide. It was developed by Eli Lilly and approved by the FDA in 2014.
- Trulicity is administered once weekly by subcutaneous injection using a prefilled pen injector. The usual starting dose is 0.75 mg.
- By mimicking the glucose-regulating effects of the incretin hormone GLP-1, Trulicity helps lower A1c levels, fasting blood sugar, and body weight.
- Clinical trials found Trulicity was effective as a stand-alone therapy or when combined with other diabetes medications like metformin.
- Potential side effects include nausea, diarrhea, vomiting, abdominal pain, headache, fatigue, dizziness, and low blood sugar.
- Trulicity has a boxed warning about the risk of thyroid tumors, including medullary thyroid carcinoma. It should not be used in people with these tumors.
- Trulicity is contraindicated in those with a personal/family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2.
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Uses Of Trulicity
Here are some of the main uses and indications for the diabetes medication Trulicity (dulaglutide): Buy Trulicity online
- Type 2 diabetes – Trulicity is approved to improve blood sugar control in adults with type 2 diabetes, either by itself or combined with other glucose-lowering medications like metformin.
- Cardiovascular disease – Clinical trials showed Trulicity reduced the risk of major cardiovascular events like heart attack, stroke, and cardiovascular death in people with type 2 diabetes who have established cardiovascular disease.
- Weight loss – Trulicity often leads to modest weight loss in patients with type 2 diabetes, likely due to its appetite-suppressing effects. This can further improve diabetes management.
- A1C reduction – Trulicity has been shown to lower A1C levels (a measure of long-term blood sugar control) in people with type 2 diabetes in a clinically significant way.
- Fasting plasma glucose – Trulicity reduces elevated fasting blood glucose levels when used alone or combined with common oral diabetes medications.
- Pre-diabetes – While not FDA-approved for this use, Trulicity may help prevent or delay the onset of type 2 diabetes in those diagnosed with prediabetes.
- Obesity – Trulicity is being studied as a potential treatment for chronic weight management in obese adults without diabetes. Results are promising so far.
- Kidney disease – Trulicity has shown benefits for patients with moderate diabetic kidney disease to improve glycemic control.
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Here are some tips on how to properly administer and use the diabetes medication Trulicity (dulaglutide): Buy Trulicity online
- Trulicity comes in a single-dose, disposable auto-injector pen that is injected once weekly under the skin (subcutaneous injection).
- Common injection sites include the abdomen, thigh, or upper arm. The pen needle is very thin and short so the injection is typically painless.
- Follow the detailed instructions in the medication guide for priming and dialing the correct dose on the pen device. Your doctor will prescribe the dosage.
- Start with 0.75 mg injected once weekly. Your doctor may increase the dosage to 1.5 mg once weekly if needed for blood sugar control.
- The injection can be administered any time of day, with or without meals. However, be consistent and pick the same day/time each week.
- Rotate injection sites each week – for example, switch between abdomen, thighs, and arms. This allows injection sites time to recover.
- Dispose of used pens immediately after injection in a sharps disposal or puncture-proof container. Never reuse or share needles.
- Store unused pens in the refrigerator before first use. After opening, pens can be stored at room temperature for 14 days.
- Monitor blood sugar levels and watch for side effects like nausea, vomiting, abdominal pain, or low blood sugar.
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Here are some of the key benefits of using Trulicity (dulaglutide) for type 2 diabetes: Buy Trulicity online
- Lowers A1C levels – Clinical trials showed Trulicity reduces hemoglobin A1c in a clinically meaningful way compared to placebo or other diabetes medications. This improves long-term blood sugar control.
- Weight loss – Patients using Trulicity typically experience modest weight loss of around 2-5 lbs on average. This can further improve diabetes management.
- Lowers fasting blood glucose – Trulicity reduces fasting plasma glucose levels when used by itself or combined with metformin, glimepiride, or insulin.
- Cardiovascular benefits – Studies found that Trulicity reduces the risk of major adverse cardiovascular events in diabetics at high CV risk.
- Well-tolerated – Trulicity has relatively low discontinuation rates due to GI side effects like nausea, which tend to diminish over time.
- Convenient weekly dosing – Only needing one injection per week may improve compliance compared to daily injections.
- Alternative treatment option – Trulicity adds another GLP-1 receptor agonist option for type 2 diabetics needing better blood sugar control.
- Lasts up to 5 days – Dulaglutide stays in the system for several days, providing sustained glycemic control throughout the week.
- Doesn’t increase hypoglycemia risk – Trulicity does not by itself increase the risk of low blood sugar compared to placebo.
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Effects Of Trulicity
Trulicity (dulaglutide) is a GLP-1 receptor agonist that works to lower blood sugar in multiple ways. Here are the main effects and actions of Trulicity: Buy Trulicity online
- Increases insulin release – Trulicity stimulates the pancreas to release more insulin after meals when blood sugar levels are elevated. This promotes glucose uptake into cells.
- Slows digestion – Trulicity slows gastric emptying and intestinal motility, which prevents blood sugar from rising too fast after meals.
- Suppresses glucagon – Trulicity reduces the secretion of glucagon, a hormone that signals the liver to release stored glucose. This lowers hepatic glucose output.
- Enhances satiety – By acting on appetite centers in the brain, Trulicity dulls appetite, leading to reduced caloric intake and potential weight loss.
- Promotes weight loss – The combined effects of Trulicity lead to modest weight loss through reduced food intake, often 2-5 lbs throughout treatment.
- Lowers blood pressure – Trulicity has been shown to slightly reduce systolic blood pressure levels.
- Improves cholesterol – Trulicity can lower LDL cholesterol and triglycerides while raising HDL cholesterol.
- Increases heart rate – Trulicity causes a mild increase in heart rate of around 2-4 beats per minute on average.
- Risk of thyroid tumors – Trulicity has a boxed warning regarding thyroid tumor risk, including medullary thyroid carcinoma.
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