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Insulin lispro, sold under the brand name Humalog among others, is a type of insulin used to treat type 1 and type 2 diabetes. Typically it is taken around the time of eating. It is used by injection under the skin or within an insulin pump. The onset of effects naturally occurs within 30 minutes and lasts about 5 hours. Buy Humalog insulin online.
Here are some critical facts about Humalog insulin:
- Humalog is a fast-acting insulin analog used to help control blood sugar levels in diabetes. It was the first insulin analog approved for use in the United States.
- It is manufactured by Eli Lilly and Company. Humalog works more rapidly than regular short-acting insulin.
- Humalog starts working within 15 minutes, peaks in 1 to 1.5 hours and lasts for 2 to 4 hours in the body. This provides faster coverage for mealtime spikes.
- Humalog is a clear, sterile solution that comes in vials and prefilled pens for subcutaneous injection. It should be stored in the refrigerator until first use.
- Humalog can be used by people with both type 1 and type 2 diabetes to help manage blood glucose. It is often prescribed alongside a long-acting insulin.
- Dosage needs to be individualized based on factors like diet, activity, stress levels, and current blood sugar readings. Careful monitoring is needed.
- Potential side effects of Humalog are similar to regular insulin and include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, and weight gain.
- Humalog is contraindicated in patients with hypoglycemia unawareness and hypersensitivity to Humalog or any of its excipients.
Let me know if you need any more details on the proper administration, dosing, side effects, or other aspects of using Humalog insulin. I’m happy to provide more information.
Use Of Humalog
Here are some of the main uses and situations where Humalog insulin is commonly prescribed:
- Mealtime dosing – Humalog is usually injected right before eating a meal or snack, or within 20 minutes after starting a meal. This controls blood sugar spikes from carbohydrate intake.
- Correcting high blood sugars – Humalog can be used to lower high blood glucose levels back to the target range. This is called taking a correction dose.
- In insulin pumps – Humalog is one of the main rapid-acting insulins used in insulin pumps to provide both basal and bolus doses.
- For diabetes types 1 and 2 – Both type 1 diabetics who make no insulin and type 2 diabetics who become insulin resistant can use Humalog.
- To cover glucose released by the liver – In addition to covering meal carbohydrates, Humalog also helps manage the glucose the liver releases.
- During illness – When sick, the body releases hormones that make blood sugar rise. Humalog doses may need adjustment to cover illness-related blood glucose spikes.
- Prior to exercise – Some take a reduced dose of Humalog before exercise to help prevent hypoglycemia that can occur with activity.
- In children – Humalog is approved for use in children ages 3 and older with type 1 diabetes. Dosing is tailored to age and weight.
- During pregnancy – Pregnant women need tight blood sugar control. Humalog allows quick adjustment around meals and with activity.
Let me know if you need any clarification on how Humalog is used to treat diabetes!
How to use Humalog
Here are some tips for properly using and injecting Humalog insulin:
- Humalog is injected subcutaneously (under the skin) into areas such as the abdomen, thighs, upper arms, or buttocks. Rotate injection sites.
- It can be used with syringes, insulin pens, or insulin pumps. Be sure to follow the manufacturer’s instructions for your injection method.
- Humalog should be taken within 15 minutes before or right after starting a meal. This controls the blood sugar spike that happens after eating.
- For high blood sugar correction, Humalog can be taken anytime. Recheck levels in 1-3 hours to see if additional insulin is needed.
- Humalog starts working very quickly, so it’s important to time injections properly with meals.
- Dosage needs to be adjusted based on blood sugar testing results, carbohydrate intake, activity, illness, stress, etc. Work with your healthcare provider.
- Don’t reuse needles or share insulin pens. Properly dispose of sharps after each use.
- Before use, gently roll the vial, pen, or cartridge to re-suspend the insulin without creating bubbles. Do not shake vigorously.
- Store unopened Humalog in the refrigerator between 36-46°F until the expiration date. Opened pens or vials can be kept at room temperature for 28 days.
Let me know if you have any other questions about properly injecting and handling Humalog! Proper technique and dosing is key for managing diabetes.
Benefits Of Humalog
Here are some of the key benefits of using Humalog insulin:
- Rapid onset – Humalog starts working within 15 minutes after injection, faster than regular short-acting insulins. This provides quick coverage for meals.
- Short duration – Humalog lasts just 2-4 hours before wearing off compared to up to 6 hours for regular insulin. This allows greater flexibility in meal timing.
- More physiologic – Humalog better mimics the body’s normal insulin response after eating compared to older insulins.
- Flexible dosing – Due to its quick action, Humalog doses can be precisely matched to current blood sugar levels and carbohydrate intake.
- Convenience – Humalog is available in vials, pens, and cartridges for use in pumps for flexible diabetes management.
- Lower hypoglycemia risk – Studies show Humalog has less risk of post-meal hypoglycemia compared to regular short-acting insulin.
- Approved for children – Humalog can be used in pediatric type 1 diabetes patients ages 3 and older when doses are properly adjusted.
- Can be mixed with long-acting insulin – Humalog can be mixed in the same syringe with long-acting insulins like Lantus with proper timing.
- Improved post-meal control – Clinical studies demonstrate Humalog provides better control of blood glucose spikes after meals.
- Can be used in insulin pumps – Humalog is one of the most commonly used rapid-acting insulins in pump therapy.
Let me know if you need any more details on the advantages of using Humalog insulin!
Effects Of Humalog
Here are some of the key effects and actions of Humalog insulin in the body:
- Lowers blood glucose – The primary effect of Humalog is to rapidly lower high blood glucose levels by facilitating glucose uptake into cells.
- Increases glucose uptake – Humalog binds to insulin receptors and activates the GLUT4 glucose transporter, allowing glucose to leave the bloodstream and enter cells.
- Humalog suppresses hepatic glucose output and inhibits the liver from releasing stored glucose, helping control fasting and post-meal blood sugars.
- Increases glycogenesis – Humalog increases the conversion of glucose into glycogen for storage in muscle and liver cells.
- Inhibits lipolysis – Humalog prevents the breakdown of fat (lipolysis), decreasing the release of free fatty acids into the bloodstream.
- Suppresses glucagon – Humalog suppresses the secretion of glucagon from the pancreas, preventing the liver from releasing more glucose.
- Promotes fat storage – The anabolic effects of Humalog promote the synthesis and storage of fats (lipogenesis).
- Can cause hypoglycemia – Humalog lowers blood sugar in a dose-dependent manner, so too high a dose can result in hypoglycemia.
- Causes weight gain – The blood glucose lowering effects of Humalog can result in some weight gain with long-term use.
- Starts working in 15 minutes – The rapid onset allows Humalog to cover mealtime spikes in blood sugar right after eating.
Let me know if you need any clarification or have additional questions on how Humalog acts in the body!
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